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Min Chen
Phone number: 86-531-88366078
Fax number: 
E-mail: chenmin@sdu.edu.cn
Title: Professor

EDUCATION

Ph.D College of Biological Sciences, China Agricultural University

Master College of Plant Protection, Shandong Agricultural University

Bachelor College of Plant Protection, Shandong Agricultural University

WORK EXPERIENCE

2014.9-present

Professor, State Key Laboratory for Microbial Technology (SKLMT), Department of Microbiology, School of Life Sciences, Shandong University, Shandong University, Jinan, China

2015.1-2016.1

Postdoctoral Researcher, Department of Medicine, Queen’s University, Kingston, CAN

2006.9-2014.9

Associate professor, State Key Laboratory for Microbial Technology (SKLMT), Department of Microbiology, School of Life Sciences, Shandong University, Shandong University, Jinan, China

2008.1-2009.1

Postdoctoral Researcher, Department of Biochemistry, The Ohio State University, Columbus, USA

2003.7-2006.8

Lecturer, State Key Laboratory for Microbial Technology (SKLMT), Department of Microbiology, School of Life Sciences, Shandong University,, Shandong University, Jinan, China

RESEARCH INTERESTS

1. glycoscinece in microbiology

2. enzymes synthesis the oligosaccharide associated with tumor

3. Vaccine

RESEARCH PROGRAMS

PI

1 Research on O157:H7 glycoprotein-conjugated vaccine, supported by NSF of China, 2013 (Project number 31270983)

2 Research on PglB based Glycoprotein conjugated vacccine, supported by NSF of China, 2010 (Project number 31070824)

3 Research on transgenitic plant based vacccine of O157:H7, , supported by Department of

public health Foundation of Shandong province. 2007

4 Modification the glycosylation of the IFN-β, supported by Foundation for OutstandingYoung Scientist of Shandong province. 2005 (Project number 2005BS02015)

Cooperate

1 National Major Scientific and Technological Special Project for

“Significant New Drugs Development, 2012, (Project number 2012ZX09502001-005)

2 Biological and chemistry research on the tumor associate polysaccharides,

Supported by 973 program, 2012, (Project number 2012CB822100)

3 The key technology and product development in Carbohydrate Engineering, 2012,

Supported by 863 program (Project number 2012AA021500)

4 Expression of medicinal glycoprotein in modified Escherichia coli system,

Supported by the Keygrant Project of Chinese Ministry of Education.( Project number No313033)

SELECTED PUBLICATIOS

1. Wenjing Shang, YafeiZhai, Zhongrui Ma, Gongjin Yang, Yan Ding, Donglei Han,, Jiang Li, Houcheng Zhang, Jun Liu,Peng George Wang, Xian-wei Liu,*,Min Chen*,Production of human blood group B antigen epitopeconjugated protein in Escherichia coliandandutilization of the adsorptionblood group B antibody,Microbial Cell Factories (2016) 15:138

2 Zhang H, Wang B, Ma Z, Wei M, Liu J, Li D, Zhang H, Wang PG, Chen M l-Rhamnose Enhances the Immunogenicity of Melanoma-Associated Antigen A3 for Stimulating Antitumor Immune Responses, Bioconjug Chem. 2016 Apr 20;27(4):1112-8.

3 Xiongjian Rao, Xiaotao Duan, , Weimin Mao, , Xuexia Li, Zhonghua Li1, , Qian Li, Zhiguo Zheng, Haimiao Xu, Min Chen, Peng G. Wang, Yingjie Wang, Binghui Shen & Wen Yi , O-GlcNAcylation of G6PD promotes the pentose phosphate pathway and tumor growth,Nature Communications, 2015,| 6:8468

4 Ma Z, Zhang H, Shang W, Zhu F, Han W, Zhao X, Han D, Wang PG, Chen M* Glycoconjugate Vaccine Containing Escherichia coli O157:H7 O-antigen Linked with Maltose-binding Protein Elicits Humoral and Cellular Responses,.PLoS One. 2014 Aug 19;9(8):e105215.

5 Xueer Zhao, Yang Zou, Mengyang Xue, Zhongrui Ma, Shuaishuai Wang ,Peng George Wang , Min Chen*,A one-pot approach to bio-synthesize globotriose and its derivatives from simpler substrates, European Journal of Medicinal Chemistry 80 (2014) 423-427

6 Jun Liu, Yang Zou , Mengyang Xue, Lan Jin, Xueer Zhao,Junkai Dong, Wenjun Wang, Jie Shen, Peng George Wang, Min Chen*,One-pot three-enzyme catalyzed synthesis of UDP-sugars and their derivatives,Glycoconjugate Journal,2013,30:(4)397

7 Jun Liu, Yang Zou , Wanyi Guan, Yafei Zhai, Mengyang Xue, Lan Jin, Xueer Zhao,Junkai Dong, Wenjun Wang, Jie Shen, Peng George Wang, Min Chen *,Biosynthesis of nucleotide sugars by a promiscuous UDP-sugar pyrophosphorylase from Arabidopsis thaliana (AtUSP) ,Bioorganic & Medicinal Chemistry Letters 23 (2013) 3764–3768

8 Yang Zou, Mengyang Xue, Wenjun Wang,_, Li Cai, Leilei Chen, Jun Liu, Peng George Wang,Jie Shen, Min Chen*,One-pot three-enzyme synthesis of UDP-Glc, UDP-Gal, and their derivatives,Carbohydrate Research 373 (2013) 76–81

9 Yang Zou, Wenjun Wang, Li Cai, Leilei Chen, Mengyang Xue, Xiaomei Zhang, Jie Shen, , Min Chen*, Substrate specificity of galactokinase from Streptococcus pneumoniae TIGR4 towards galactose, glucose, and their derivatives,Bioorganic & Medicinal Chemistry Letters 22 (2012), 3540-3543 2013

10Yang Zou, Zhigang Wu, Leilei Chen, Weixia Wang, Guofeng Gu,Xianwei Liu, Peng Georoge Wang, Min Chen*, An Efficient Approach for Large Scale Production of Sialyglycopeptides from Egg Yolk,Journal of Carbohydrate Chemistry,2012,436-446 J CARBOHYD CHEM

11 Min Chen, Lei-lei Chen ,Yang Zou, Mengyang Xue, Min Liang, Lan Jin, Wan-yi Guan,Jie Shen, Wenjun Wang, Lei Wang, Jun Liu, Peng George Wang, Wide sugar substrate specificity of galactokinase from Streptococcus pneumoniae TIGR4, Carbohydrate Research ,2011, 346, 2421–2425

12 Xian-wei Liu, Chengfeng Xia, Lei Li, Wan-yi Guan, Nicholas Pettit, Hou-cheng Zhang, Min Chen* Peng George Wang,Characterization and synthetic application of a novel b1,3-galactosyltransferase from Escherichia coli O55:H7,Bioorganic & Medicinal Chemistry,2009, 17(14): 4910-4915,

13 Jingjing Luan, Zhong Zhuang, Yan Liu, Min Chen*, Peng George Wang,Expression of EspA in Lactococcus lactis NZ9000 and the detection of its immune effect in vivo and vitro,Immunopharmacology and Immunotoxicology,(2010), 32(1), 133-140.

PATENTS

1. Na+/H+ antiporter genes and their encoded proteins, ZL02146310

2 . An enzyme that degradation of pesticide ZL200910018405.7

3. A recombinant N - glycoprotein vaccine against O157: H7 ZL 2014 10029563.3

4 A approach of sialic acid sugar peptide separation ZL 20110322663.1

5 A one-pot approach to bio-synthesize globotriose and its derivatives ZL 2014 1, 001975.0


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