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Qingsheng Qi
Phone number: 0531-88365628
Fax number: 
E-mail: qiqingsheng@sdu.edu.cn
Title: Professor


Ph.D: 1997-2001 University of Muenster, Germany

Master: 1989-1992 Shandong University, Jinan

Bachelor: 1985-1989 Shandong University, Jinan


2001-2003 University of Chemnitz, Germany, Posdoc

2003- Shandong University, Professor


1. Pathway engineering of micro-organisms towards the efficient production of useful bulk chemicals and value added compounds;

2. Investigations of the molecular mechanisms of stress response during the metabolic engineering and fermentation process in these micro-organisms;

3. Developing the metabolic and biosynthetic methods or tools for the synthetic biology


1. 2014-2017 Biosynthesis of 5-aminolevulinic acid in Escherichia coli

2. 2017-2021 Biosynthesis and regulation of NeuAc using riboswitch

3. 2014-2016 Innovation production of the key bulk chemicals


1. Peng Yang, Wenjing Liu, Xuelian Cheng, Jing Wang, Qian Wang, Qingsheng Qi: A new strategy for the production of 5-aminolevulinic acid in recombinant Corynebacterium glutamicum with high yield. Applied and Environmental Microbiology 02/2016; 82(9). DOI:10.1128/AEM.00224-16

2. Dongfang Gao, Yaqi Luan, Qian Wang, Quanfeng Liang, Qingsheng Qi: Construction of cellulose-utilizing Escherichia coli based on a secretable cellulase. Microbial Cell Factories 10/2015; 14(1). DOI:10.1186/s12934-015-0349-7

3. Peng Yang, Jing Wang, Qingsheng Qi: Prophage recombinases-mediated genome engineering in Lactobacillus plantarum. Microbial Cell Factories 10/2015; 14(1). DOI:10.1186/s12934-015-0344-z

4. Quanfeng Liang, Fengyu Zhang, Yikui Li, Xu Zhang, Jiaojiao Li, Peng Yang, Qingsheng Qi: Comparison of individual component deletions in a glucose-specific phosphotransferase system revealed their different applications. Scientific Reports 08/2015; 5. DOI:10.1038/srep13200

5. Junming Wang, Dongfang Gao, Xiaoli Yu, Wen Li, Qingsheng Qi: Evolution of a chimeric aspartate kinase for L-lysine production using a synthetic RNA device. Applied Microbiology and Biotechnology 05/2015; 99(20). DOI:10.1007/s00253-015-6615-0

6. Xinran Wang, Qian Wang, Qingsheng Qi: Identification of riboflavin: Revealing different metabolic characteristics between Escherichia coli BL21(DE3) and MG1655. FEMS Microbiology Letters 04/2015; 362(11). DOI:10.1093/femsle/fnv071

7. Pengfei Gu, Fan Yang, Tianyuan Su, Qian Wang, Quanfeng Liang, Qingsheng Qi: A rapid and reliable strategy for chromosomal integration of gene(s) with multiple copies. Scientific Reports 04/2015; 5. DOI:10.1038/srep09684

8. Quanfeng Liang, Qingsheng Qi: From a co-production design to an integrated single-cell biorefinery. Biotechnology Advances 11/2014; 32(7). DOI:10.1016/j.biotechadv.2014.08.004

9. Qianqian Zhuang, Qian Wang, Quanfeng Liang, Qingsheng Qi: Synthesis of polyhydroxyalkanoates from glucose that contain medium-chain-length monomers via the reversed fatty acid β-oxidation cycle in Escherichia coli. Metabolic Engineering 05/2014; 24. DOI:10.1016/j.ymben.2014.05.004

10. Li, Y., M. Li, X. Zhang, P. Yang, Q. Liang and Q. Qi (2013). "A novel whole-phase succinate fermentation strategy with high volumetric productivity in engineered Escherichia coil." Bioresource Technology 149: 333-340.

11. Kang J, Gu P, Wang Y, Li Y, Yang F, Wang Q, Qi Q, Engineering of an N-acetylneuraminic acid synthetic pathway in Escherichia coli. Metab Eng. 2012: S1096-7176(12)00093-6. doi: 10.1016/j.ymben.2012.09.002

12. Quan Chen, Qian Wang, Guoqing Wei, Quanfeng Liang, and Qingsheng Qi*. (2011) Production of Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with Varied Monomer Compositions in Escherichia coli from Unrelated Carbon Sources. Appl. Environ. Microbiol. doi:10.1128/AEM.00091-1

13. Zhen Kang, Yang Wang, Pengfei Gu, Qian Wang, Qingsheng Qi* (2011) Engineering Escherichia coli for efficient production of 5-aminolevulinic acid from glucose. Metab. Eng. doi:10.1016/j.ymben.2011.05.003

14. Geng Y, Wang S, Qi Q* (2010) Expression of Active Recombinant Human Tissue-Type Plasminogen Activator Using in vivo Polyhydroxybutyrate Granule Display. Applied Environmental Microbiology. doi:10.1128/AEM.01543-10


More than 10 microbial technologies were patented.

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