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Doctoral tutor
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Doctoral tutor > Zoology  
Xiangguo Liu
Phone number: 86-531-88364330
Fax number: 
E-mail: xgliu@sdu.edu.cn
Title: Professor

EDUCATION

Ph.D 1997-2000 Institute of Microbiology, CAS Microbiology

Master 1994-1997 Shandong University School of Life Sciences Cell Biology

Bachelor 1990-1994 Shandong University Biology

WORK EXPERIENCE

2008.10-present Shandong University School of Life Sciences Professor

2003.9-2008.10 Emory University Winship Cancer Institute Postdoc

2002.11-2003.8 University of Florida College of Medicine Postdoc

2000.9-2002.11 Peking University Health Science Center Postdoc

RESEARCH INTERESTS

1. Apoptosis and autophagy in cancer cells

2. Cancer metastasis

3. Anti-cancer compound screening and molecular therapeutics

AWARDS

1. New Century Excellent Talent in University, 2009

2. Shandong Distinguished Young Scholar in Natural Science, 2010

SELECTED PUBLICATIONS

1.Li T, Su L, Lei Y, Liu X, Zhang Y, Liu X*. DDIT3 and KAT2A Proteins Regulate TNFRSF10A and TNFRSF10B Expression in Endoplasmic Reticulum Stress-mediated Apoptosis in Human Lung Cancer Cells. J Biol Chem. 2015; 290:11108-18.

2.Li T, Su L, Zhong N, Hao X, Zhong D, Singhal S, Liu X*. Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells. Autophagy. 2013; 9:1057-1068.

3.Xu L, Su L, Liu X*. PKCδ Regulates Death Receptor 5 Expression Induced by PS-341 through ATF4- ATF3/CHOP axis in Human Lung Cancer Cells. Mol Cancer Ther. 2012; 11(10):2174-82.

4.Su L, Liu G, Hao X, Zhong N, Zhong D, Liu X*, Singhal S. Death Receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. Eur. J. Cancer. 2011;47: 2471-8.

5.Liu X, Su L*, Liu X*. Loss of CDH1 Up-regulates Epidermal Growth Factor Receptor via Phosphorylation of YBX1 in Non-small Cell Lung Cancer cells. FEBS Lett. 2013; 587:3995-4000.

6.Liu X, Yue P, Chen S, Hu L, Lonial S, Khuri FR, Sun SY. The Proteasome Inhibitor PS-341 (Bortezomib) Up-Regulates DR5 Expression Leading to Induction of Apoptosis and Enhancement of TRAIL-Induced Apoptosis Despite Up-Regulation of c-FLIP and Survivin Expression in Human NSCLC Cells. Cancer Res. 2007;67:4981-8.

7.Liu X, Yue P, Schonthal AH, Khuri FR, Sun SY. Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells. Cancer Res. 2006; 66:11115-9.

8.Liu X, Yue P, Khuri FR, Sun SY. Decoy receptor 2 (DcR2) is a p53 target gene and regulates chemosensitivity. Cancer Res. 2005; 65: 9169-75.

9.Liu X, Yue P, Zhou Z, Khuri FR, Sun SY. Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. J Natl Cancer Inst. 2004; 96: 1769-80.

10.Liu X, Yue P, Khuri FR, Sun SY. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Res. 2004; 64: 5078-83.


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