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Doctoral tutor
· botany
· Zoology
· microbiology
· ecology
Master Tutor
· botany
· Zoology
· microbiology
· ecology
Master Tutor > microbiology  
Haoxin Wang
Phone number: 86-531-88362350
Fax number: 
E-mail: wanghaoxin@sdu.edu.cn
Title: Lecturer


Ph.D: Kunming Institute of Botany, Chinese Academy of Sciences (Botany, 2001/9 - 2008/1)

Bachelor: Anhui University (Biology, 1997/9 - 2001/7)


1、2010/6 – Now Shandong University Assistant Professor

2、2008/3 - 2010/3 Xiamen University Postdoc.


1. Discovery of novel natural products from actinobacteria.

2. Biosynthetic mechanism of bioactive natural products.

3. Synthetic biology of natural products.


1. Rational discovery of new AHBA-containing natural products,National Natural Science Foundation of China (NSFC), 31570039, 2016/01-2019/12, ¥650,000

2. Discovery of novel ansamycins from cryptic gene cluster, National Natural Science Foundation of China (NSFC), 31100079, 2012/01-2014/12, ¥250,000

3. Discovery novel polyketides through heterologous expression of biosynthetic gene cluster, Independent Innovation Foundation of Shandong University (IIFSDU), 2010TS072, 2010/06-2012/12, ¥70,000

4. Function of ansamycin biosynthetic gene cluster isolated from metagenome of plant microbiota, China Postdoctoral Science Foundation funded project (CPSF), 20090450840, 2009/03-2010/03, ¥30,000


1. G. Shi#; N. Shi#; Y. Li; W. Chen; J. Deng; C. Liu; J. Zhu; H. Wang*; Y. Shen*, d-Alanylation in the Assembly of Ansatrienin Side Chain is Catalyzed by a Modular NRPS. ACS chemical biology 2016, 11(4), 876-881.

2. S. Li#; Y. Li; C. Lu; J. Zhang; J. Zhu; H. Wang*; Y. Shen*, Activating a Cryptic Ansamycin Biosynthetic Gene Cluster To Produce Three New Naphthalenic Octaketide Ansamycins with n-Pentyl and n-Butyl Side Chains. Org Lett 2015, 17, 3706-9.

3. C. Liu#; J. Zhu; Y. Li; J. Zhang; C. Lu; H. Wang*; Y. Shen*, In Vitro Reconstitution of a PKS Pathway for the Biosynthesis of Galbonolides in Streptomyces sp. LZ35. Chembiochem 2015, 16, 998-1007.

4. C. Xie#; J. Deng; H. Wang*, Identification of AstG1, A LAL family regulator that positively controls ansatrienins production in Streptomyces sp. XZQH13. Curr Microbiol 2015, 70, 859-64.

5. J. Zhu#; W. Chen; Y. Li; J. Deng; D. Zhu; J. Duan; Y. Liu; G. Shi; C. Xie; H. Wang*; Y. Shen*, Identification and catalytic characterization of a nonribosomal peptide synthetase-like (NRPS-like) enzyme involved in the biosynthesis of echosides from Streptomyces sp. LZ35. Gene 2014, 546, 352-8.

6. S. Li#; H. Wang#; Y. Li; J. Deng; C. Lu; Y. Shen*, Biosynthesis of hygrocins, antitumor naphthoquinone ansamycins produced by Streptomyces sp. LZ35. Chembiochem 2014, 15, 94-102.

7. H. Wang#; Y. Chen; L. Ge; T. Fang; J. Meng; Z. Liu; X. Fang; S. Ni; C. Lin; Y. Wu; M. Wang; N. Shi; H. He; K. Hong; Y. Shen, PCR screening reveals considerable unexploited biosynthetic potential of ansamycins and a mysterious family of AHBA-containing natural products in actinomycetes. J Appl Microbiol 2013, 115, 77-85.

8. C. Lu#; Y. Li#; J. Deng#; S. Li; H. Wang*; Y. Shen*, Hygrocins C-G, cytotoxic naphthoquinone ansamycins from gdmAI-disrupted Streptomyces sp. LZ35. J Nat Prod 2013, 76, 2175-2179.

9. Y. Jiang#; H. Wang#; C. Lu; Y. Ding; Y. Li; Y. Shen, Identification and characterization of the cuevaene A biosynthetic gene cluster in Streptomyces sp. LZ35. Chembiochem 2013, 14, 1468-1475.

10. H. Wang#; Z. Geng; Y. Zeng; Y. Shen, Enriching plant microbiota for a metagenomic library construction. Environ Microbiol 2008, 10, 2684-2691


1. Haoxin Wang,Ying Zeng,Yuemao Shen,The Protocol of plant microbiota preparation,2007.3.19-2027.3.19,China,ZL200710065724.4。

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