刘怀伟-山东大学生命科学学院
硕士生导师
刘怀伟
作者:   时间:2017-12-12   点击数:

刘怀伟

电 话:传 真:E-Mail:liuhuaiwei@sdu.edu.cn

教育背景

1999/09—2003/07 山东师范大学, 生命科学学院,生命科学学士

2005/09— 2010/07 山东大学,生命科学学院,微生物学博士学位

工作经历

2011/04— 2013/12 韩国 明知大学(Myongji University), 博士后

2014/01— 2015/06 美国 伊利诺伊香槟分校(University of Illinois at Urbana-Champaign),博士后

2015/06— 山东大学,生命科学学院,副研究员

研究方向

环境微生物学、微生物生理与生化、代谢工程与合成生物学

近年所发表的论文(2011—2017)

1. Li H, Li J, Lü C, Xia Y, Xin Y, Liu H, Xun L,Liu H*(2017) FisR activates σ54 -dependent transcription of sulfide-oxidizing genes in Cupriavidus pinatubonensis JMP134.Mol Microbiol. 105(3):373-384

2. Xin Y, Liu H, Cui F,Liu H, Xun L* (2016) Recombinant Escherichia coli with sulfide:quinone oxidoreductase and persulfide dioxygenase rapidly oxidises sulfide to sulfite and thiosulfate via a new pathway. Environ Microbiol. 18(12):5123-5136.

3. Liao C1, Seo S, Celik V,Liu H, Kong W, Wang Y, Blaschek H, Jin Y, and Lu T* (2015)

An integrated, systems metabolic picture of the acetone-butanol-ethanol fermentation by Clostridium acetobutylicum. Proc. Natl. Acad. Sci. 112: 8505–8510.

4.Liu H1, Lu T* (2015) Autonomous production of 1,4-butanediol via a de novo biosynthesis pathway in engineered Escherichia coli. Metab Eng. 29:135-41.

5.Liu H1, Wang Y1, Tang Q, Kong W, Chung WJ, Lu T* (2014) MEP pathway-mediated isopentenol production in metabolically engineered Escherichia coli. Microb Cell Fact. 13: 135.

6. Ramos KR1, Valdehuesa KN,Liu H, Nisola GM, Malihan LB, Lee WK, Chung WJ* (2014) Combining De Ley-Doudoroff and Methylerythritol phosphate pathways for enhanced isoprene biosynthesis from D-galactose. Bioprocess Biosyst Eng. 37: 2505-2513.

7.Liu H1, Valdehuesa KN, Ramos KR, Nisola GM, Malihan LB, Lee WK, Chung WJ* (2014) L-arabonate and D-galactonate production by expressing a versatile sugar dehydrogenase in metabolically engineered Escherichia coli. Bioresour Technol. 155: 455-459.

8.Liu H1, Ramos KR, Valdehuesa KN, Nisola GM, Malihan LB, Lee WK, Park SJ, Chung WJ* (2013) Combination of Entner-Doudoroff pathway with MEP pathway increases isoprenoid production in engineered Escherichia coli. PLoS One. DOI 10.1007/s00449-013-1003-6.

9. Valdehuesa KN1,Liu H1, Ramos KR, Park SJ, Nisola GM, Malihan LB, Lee WK, Chung WJ* (2013) Direct bioconversion of D-xylose to 1,2,4-butanetriol in an engineered Escherichia coli host. Process Biochem. DOI: http://dx.doi.org/10.1016/j.procbio.2013.10.002 (Co-first author).

10.Liu H1, Ramos KR, Valdehuesa KN, Nisola GM, Malihan LB, Lee WK, Park SJ, Chung WJ* (2013) Metabolic engineering of Escherichia coli for biosynthesis of D-galactonate. Bioprocess Biosyst Eng. DOI: 10.1007/s00449-013-1003-6.

11. Valdehuesa KN1,Liu H, Nisola GM, Chung WJ, Lee SH, Park SJ* (2013) Recent advances in the metabolic engineering of microorganisms for the production of 3-hydroxypropionic acid as C3 platform chemical, Appl Microbiol Biotecnol. 97, 3309–3321.

12.Liu H1, Ramos KR, Valdehuesa KN, Nisola GM, Lee WK, Chung WJ* (2013) Biosynthesis of ethylene glycol in Escherichia coli. Appl Microbiol Biotechnol. 97, 3409–3417.

13.Liu H1, Valdehuesa KN, Nisola GM, Ramos KR., Chung WJ* (2012) High yield production of d-xylonic acid from D-xylose using engineered Escherichia coli. Bioresour Technol. 115, 244–248

近年所发表的专利

1. Wook-Jin Chung,Huaiwei Liu, Kris Nino Gomez Valdehuesa, Kristine Rose Medina Ramos, Mi-Deok Han. Recombinant Escherichia coli producing D-xylonic acid from D-xylose and method for producing D-xylonic acid using the same. US patent 20130084612 A1

2. Wook-Jin Chung,Huaiwei Liu. Microorganisms producing ethane-1, 2-diol, and method using same for producing ethane-1, 2-diol,2013.02.05,WIPO,PCT/KR2013/000917

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